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About synapse

Showing all 56 questions under this category.

Q:Can you handle products requiring strict temperature control (Cold Chain), such as 2℃ to 8℃ storage?
A:

Yes. We provide secure international transportation solutions using state-of-the-art Cold Chain technology to maintain a consistent 2℃ to 8℃ environment throughout the journey.


Cold Chain Solutions & Quality Assurance

High-Performance Specialized Containers:
We utilize advanced vacuum-insulated containers (e.g., va-Q-tec) and thermal packaging designed to maintain stable temperatures for extended periods during international transit.


Real-time Temperature Monitoring:
Temperature Data Loggers can be included in your shipment to record thermal conditions throughout the flight and inland transit. This provides empirical proof of quality and ensures no temperature deviations occurred upon arrival.


GDP-Compliant Operations:
From our warehouse in Japan to your designated global destination, all handling is conducted under strict EU GDP (Good Distribution Practice) standards.


Customized Logistics Design:
We propose the optimal packaging configuration based on the shipping route, estimated transit time, and the climatic conditions of the destination. Please consult with our specialists during the quotation process for specific requirements.

#GDP-Compliant Operations#Customized Logistics Design
Q:What are PMDA Standards, and what specific requirements do they include?
A:

'PMDA Standards' is a collective term for the regulations and guidelines established by the Pharmaceuticals and Medical Devices Agency (PMDA) and the Ministry of Health, Labour and Welfare (MHLW). These standards are designed to ensure the Quality, Efficacy, and Safety of all pharmaceuticals and medical devices distributed within Japan.


Structural Understanding of the Regulatory Framework


PMDA Standards encompass a comprehensive set of rules covering the entire product lifecycle:


  1. Standards for Manufacturing and Quality Control (GxP):

    GMP (Good Manufacturing Practice): Standards for manufacturing control and quality control of products.

    GQP (Good Quality Practice): Standards for quality control of the marketing authorization holder (MAH).


  2. Benchmarks for Approval and Conformity Assessment:

    The Japanese Pharmacopoeia (JP): The official compendium of standards for the properties and quality of drugs.

    Essential Principles: Requirements regarding the safety and performance that medical devices must satisfy.

    Individual Approval/Certification Standards: Specific review guidelines established for particular diseases or product categories.


  3. Post-Marketing Safety Management

    GVP (Good Vigilance Practice): Standards for post-marketing safety management to monitor adverse effects and ensure patient safety.


Professional Advice for Importers and Sourcing Partners

  • Conformity for the Japanese Market: When introducing overseas products to Japan, proof of conformity to these PMDA Standards is mandatory. In particular, the GMP Inspection of manufacturing facilities is a critical and rigorous step in the approval process.

  • Tracking the Latest Updates: Standards and guidelines are frequently updated to align with scientific progress. For the latest review policies regarding a specific product, we recommend checking the official PMDA website or consulting our regulatory specialists via Messages.

#Essential Principles#Certification Standards#Tracking the Latest Updates
Q:What is "synapse"? (https://synapse.net)
A:

'synapse' is a specialized B2B platform for Japanese pharmaceutical information and procurement, operated by Kosei Pharmaceutical Co., Ltd. It serves as a digital bridge between the Japanese drug market and global healthcare professionals.


Service Overview & Core Functions

  • Pharmaceutical Database:

    A comprehensive, English-language database of Japanese medicines, searchable by Active Ingredient (USAN/INN), Therapeutic Class, or Manufacturer.
  • Key Features

    1. Search & Research: Accurate, professional-grade research for Japanese pharmaceutical products.
    2. Request for Quote (RFQ): Fast quotation generation via the 'My List' feature.
    3. One-Stop Procurement: Seamless transition from information browsing to secure online ordering for registered members.

Target Audience

Specifically designed for overseas medical professionals, including Doctors, Pharmacists, Hospitals, and Licensed Pharmaceutical Wholesalers.

#Key Features#Search & Research#One-Stop Procurement
Q:What kind of company is Kosei Pharmaceutical Co., Ltd.?
A:

Kosei Pharmaceutical Co., Ltd. is a premier Japanese pharmaceutical wholesaler and specialized trading house established in 1952. With over 70 years of history, the company is a global leader in supplying high-quality Japanese pharmaceuticals to the international market.


Corporate Profile & Strategic Strengths

Core Business Integration:

Combines a robust domestic foundation (trading with approx. 12,000 medical institutions in Japan) with an extensive global supply chain reaching over 50 countries.

Proven Track Record:

Maintains a vast network of over 70,000 corporate and medical partners worldwide.

Specialized Expertise

  • Exporting Japanese-origin pharmaceuticals.

  • Sourcing Orphan Drugs and Oncology medications.

  • Operation of the global procurement platform 'synapse'.

Corporate Governance:

A wholly-owned subsidiary of Clinifer Co., Ltd. (Tokyo Stock Exchange: 432A). This ensures the highest standards of financial transparency and regulatory compliance.

#Proven Track Record#Specialized Expertise#Corporate Governance
Q:Can I easily place a "Re-order" for a product I have purchased before?
A:

Yes. You can quickly Re-order products from your transaction history within your 'My Account' dashboard.


Re-order Specifications & Workflow


  • Eligibility:

    Products from order history confirmed within the last 3 months are eligible for the simplified Re-order function.


  • Steps to Re-order

    1. Navigate to the 'Order History' page.
    2. Select the relevant past order.
    3. Click 'Re-order' or 'Add to Cart' to initiate the checkout process.

  • Important Considerations

    • Inventory Fluctuations: Availability may differ from your previous order. The system will perform a real-time check upon re-ordering.

    • Supply Verification: For products marked as 'Shortage' or those with unstable supply, a new confirmation of lead time and availability may be required, even for repeat orders.

    • Orders Older Than 3 Months: If the product was purchased more than 3 months ago, please initiate a new Request for Quote (RFQ) via the search engine or your 'My List' to ensure current pricing and stock accuracy.

    #Steps to Re-order#Supply Verification#Orders Older Than 3 Months
Q:What kind of platform is "synapse"?
A:

'synapse' is a premier global information and procurement platform for healthcare professionals, operated by Kosei Pharmaceutical Co., Ltd. It is designed to bridge the gap between the Japanese pharmaceutical market and the international medical community.


Core Value Propositions

Japan's First English Pharmaceutical Database:
Provides comprehensive access to Japanese drug data in English. Users can perform a Multifaceted Search based on Active Ingredients (API/INN), Therapeutic Category, Manufacturer, and specialized clinical tags.


Evidence-Based Research:
By removing language barriers, the platform serves as a high-precision research source. Overseas experts can access accurate, evidence-based data on Japanese medicines, including dosage, indications, and clinical properties.


One-Stop Digital Procurement:
Enables a seamless workflow from information gathering to acquisition. Users can add products to 'My List' to initiate a Request for Quote (RFQ) and finalize an Order entirely within the digital platform.


Target Audience (Eligible Users)

Specifically built for international medical and pharmaceutical professionals, including Doctors, Patients (with valid prescriptions), Pharmacists, Hospitals, and Licensed Wholesalers who seek to source high-quality Japanese pharmaceuticals safely and efficiently.

#Evidence-Based Research#One-Stop Digital Procurement#Eligible Users
Q:What kind of company is Kosei Pharmaceutical Co., Ltd.?
A:

Kosei Pharmaceutical Co., Ltd. is a long-established Japanese pharmaceutical wholesaler and specialized trading house headquartered in Osaka, established in 1952. With over 70 years of heritage, the company is a global leader that integrates a robust domestic foundation with the cutting-edge digital platform, 'synapse.'


Corporate Attributes & Core Competencies

Proven Reliability & Market Presence:
As an independent wholesaler, we maintain a powerful network of approximately 12,000 medical institutions and pharmacies across Japan.


Pioneer in Global Distribution:
We operate 'synapse,' a proprietary cross-border platform designed to connect the Japanese pharmaceutical market with the world, serving as a vital bridge for the stable supply of high-quality medicines to global healthcare settings.


Strong Governance & Financial Stability:
As a wholly-owned subsidiary of Clinphar Inc. (Tokyo Stock Exchange: 432A), we operate with the highest standards of transparency and regulatory compliance required of a publicly-listed group.


Specialized Supply Chain Capabilities:
We offer optimized domestic and international logistics, specializing in rapid response to urgent medical needs and the handling of medications requiring strict GDP-compliant cold chain management.


Corporate Profile

  • Official Name: Kosei Pharmaceutical Co., Ltd.

  • Established: July 1952 (Over 70 years of operation)

  • Headquarters: 5th Floor, OMM Building, 1-7-31 Otemae, Chuo-ku, Osaka, Japan

  • President & CEO: Kohei Toda

  • Parent Company: Clinphar Inc. (TSE: 432A)

#Tokyo Stock Exchange#Established#Headquarters
Q:What specific medical field does "Oncology" refer to?
A:

Oncology is the branch of medicine dedicated to the diagnosis, research, and treatment of cancer (malignant tumors). Within the pharmaceutical and distribution industries, it encompasses specialized anti-cancer drugs (antineoplastics) and the advanced technologies required for their delivery.


Domain Expertise & Sourcing Criticality

Global High Demand:
Japanese-approved oncology products, including small molecule drugs and monoclonal antibodies (mAbs), are in high demand by global medical institutions due to their exceptional quality and clinical reliability.


Rigorous Quality & Logistics Control:
Oncology medications are often high-value and sensitive. They demand strict adherence to GDP (Good Distribution Practice), requiring precise temperature control and specialized handling. A secure supply chain is directly linked to patient outcomes.


Support for Precision Medicine:
As personalized medicine based on genetic mutations and biomarkers-becomes the standard of care, access to accurate, up-to-date data regarding active ingredients and specific indications is essential for oncologists.


Strategic Value of synapse.net in Oncology

Oncology is a domain where professional expertise and sophisticated logistics intersect. The combination of 'synapse's' high-precision English research capabilities and Kosei Pharmaceutical's secure international distribution infrastructure provides powerful support for cancer treatment worldwide.

#malignant tumors#antineoplastics#mAbs
Q:What are "Rare Diseases"?
A:

Rare Diseases are medical conditions that affect a very small number of individuals globally, often making diagnosis difficult and treatment options limited. With over 7,000 identified rare diseases worldwide, ensuring patient access to appropriate therapy remains one of the most critical challenges on the front lines of modern medicine.


Social Challenges & Orphan Drugs

The Diagnostic Odyssey:
Due to a lack of specialists and clinical cases, patients often face a 'diagnostic maze,' taking years to receive an accurate diagnosis. The development and distribution of Orphan Drugs (medications for rare diseases) are urgent global priorities.


Geographical Access Gaps (Drug Lag):
Effective treatments approved in one country may remain unapproved or unavailable in others, leading to a loss of life critical treatment opportunities.


Expectations for Japanese Pharmaceuticals:
High-quality rare disease medications approved under Japan's rigorous regulatory standards represent a vital lifeline for patients and physicians worldwide.


Social Mission of synapse

  • 'synapse' is dedicated to breaking down the 'information barriers' and 'logistical walls' in rare disease treatment.

  • Globalization of Information:
    By publishing data on Japanese-approved orphan drugs in English, we empower global specialists to conduct rapid, accurate research.

  • Supporting the Last Mile:
    We provide overseas medical institutions with a streamlined procurement route via 'My List' and the RFQ process. Our platform supports Expanded Access (Compassionate Use), ensuring that life-saving medicines reach the patients who need them most from a humanitarian perspective.

#Globalization of Information#Supporting the Last Mile#Drug Lag
Q:What does "Shortage" refer to in the pharmaceutical industry?
A:

In the pharmaceutical industry, a Shortage refers to a state of supply deficit, stockouts, or severe scarcity of medications. Caused by factors such as manufacturing disruptions, raw material (API) shortages, or geopolitical risks, the inability to deliver essential drugs to clinical settings has become a critical global challenge.


Supply Chain Resilience & Risk Mitigation

Information Transparency:
For international healthcare professionals, understanding the domestic supply status in Japan is vital for procurement planning. 'synapse' publishes a 'Medical Supply Information List' reflecting the latest market trends to eliminate information asymmetry.


Proactive Risk Management:
By visualizing detailed statuses such as 'Limited Shipment' or 'Supply Suspension,' we help users avoid stockout issues after ordering, ensuring high-certainty procurement.


Hub for Alternative Sourcing:
When a specific product faces a shortage, we provide rapid information on the availability of therapeutic equivalents or generic alternatives. Leveraging our extensive Japanese network, we support 'Continuity of Care' for medical facilities worldwide.


Strategic Advantage of synapse.net

In an era of supply instability, data-driven decision-making is indispensable. 'synapse' integrates Kosei Pharmaceutical's robust domestic inventory with real-time market data, serving as the most reliable supply partner in an uncertain global market.

#Proactive Risk Management#Hub for Alternative Sourcing
Q:What does it mean to have operations compliant with "EU GDP Standards"?
A:

GDP (Good Distribution Practice) refers to the international standards governing the appropriate distribution of pharmaceuticals. It is a set of rigorous rules designed to ensure that the quality, efficacy, and safety of a product are maintained throughout the entire process-from leaving the manufacturing plant to reaching the patient.


Global Standards & Quality Assurance

The 'EU Standard':The World's Gold Standard:
The GDP guidelines established by the European Union (EU) are recognized as the most stringent in the world. Compliance signifies that the following advanced management systems are in place:


Strict Temperature Control:
Real-time monitoring of temperature throughout storage and transit to prevent the degradation of active ingredients.


Full Traceability:
Complete visualization of the distribution channel to prevent the infiltration of counterfeit medicines, guaranteeing 100% product authenticity.


Maintenance of Physical Integrity: Utilization of Validated Packaging to prevent contamination or damage, operated within a specialized pharmaceutical-only delivery network.


GDP-Trained Personnel:
All operations are executed by professional staff who undergo continuous training and follow strict Standard Operating Procedures (SOPs).


Quality Commitment of synapse.net (Kosei Pharmaceutical)

Our mission is to deliver high-quality Japanese pharmaceuticals to the world while maintaining their Pharmaceutical Integrity exactly as it was at the time of manufacture. Based on the foundation of EU GDP, we provide the highest degree of reliability to medical institutions in all regions, including Asia, the Middle East, and Africa.

#s Gold Standard#Strict Temperature Control#Full Traceability
Q:What are the specific strengths of Japanese pharmaceuticals in the international market?
A:

The competitive advantage of Japanese pharmaceuticals lies in a world-class Research & Development (R&D) capability combined with 'Japan Quality'- reputation built on some of the world's most stringent quality standards. Japan is one of the few 'Major Drug-Discovery Nations' capable of developing innovative new drugs from scratch for the global market.


Four Core Competitive Advantages

Global Innovation Leadership:
Japan consistently pioneers breakthroughs in cutting-edge fields such as Oncology, Regenerative Medicine, and Biopharmaceuticals.


Excellence in Formulation & Manufacturing:
Beyond high-purity active ingredients, Japanese products excel in 'Formulation Ingenuity.' This includes enhancing patient compliance through ease of swallowing and preventing medical errors through sophisticated labeling and design.


Rigorous Approval by PMDA:
The fact that a product has passed the rigorous examination of the PMDA (Pharmaceuticals and Medical Devices Agency) serves as a premium global brand, guaranteeing the highest tiers of safety and efficacy.


Advanced Life-Science Ecosystem:
Japan possesses a robust ecosystem that rapidly translates Nobel-prize-winning basic research (e.g., iPS cells, Immune Checkpoint Inhibitors) into practical clinical applications.


Strategic Value of synapse.net

The information provided on 'synapse' is more than just a product catalog; it is an access portal to the core values of Trust, Safety, and High Purity that global buyers demand. Especially in critical, life-saving treatments, Japanese pharmaceuticals serve as the most trusted choice, supporting healthcare professionals on the global front lines.

#Rigorous Approval by PMDA
Q:What are the characteristics and benefits of Japan's Drug Pricing System (Official Price)?
A:

Pharmaceutical prices in Japan are governed by the National Health Insurance (NHI) Drug Price System, where the government determines and manages official prices. This ensures a uniquely stable market structure where high-quality pharmaceuticals are provided at transparent, standardized, and fair prices.


Economic Advantages for Global Buyers

Superior Cost-Effectiveness:
Despite clearing rigorous PMDA reviews and high manufacturing standards (GMP/GDP), Japanese pharmaceuticals remain highly cost-effective compared to other developed markets due to national price controls.


Price Transparency & Predictability:
Unlike markets with high price volatility driven by unconstrained competition, the official price system ensures stability. This allows buyers to conduct procurement with high Predictability, facilitating more accurate budgeting and inventory investment.


Inflation Resilience & Stable Supply:
The system suppresses sudden price spikes caused by external economic factors, maintaining the relative price competitiveness of Japanese products in the international market.


Incentives for Innovation:
Recent trends in the system emphasize the value of Innovative New Drugs (e.g., Oncology and Rare Diseases) while providing incentives for Supply Stability, ensuring that high-reliability products are consistently available.


Strategic Value of synapse.net

'synapse' serves as a trusted gateway that broadcasts real-time data on the latest prices and supply statuses from this highly transparent Japanese market. Backed by Japan's unique and stable regulatory framework, we offer global medical institutions both Peace of Mind and Significant Economic Advantages.

#Incentives for Innovation
Q:How does the "Weak Yen" (Yen depreciation) trend benefit international pharmaceutical buyers?
A:

The current 'Weak Yen' environment presents a Strategic Export Opportunity for international buyers, allowing them to procure high-quality Japanese pharmaceuticals under exceptionally favorable economic conditions.


Four Key Economic Advantages

Increased Purchasing Power:
As the Japanese Yen depreciates, procurement costs in foreign currencies (e.g., USD, EUR) decrease relatively. This allows buyers to secure a larger volume of products within the same budget or reallocate funds toward high-value, cutting-edge medications like Oncology treatments.


Synergy with the NHI Price System:
Japan's unique 'Official Drug Pricing' prevents the rapid domestic price spikes often seen in other markets due to inflation. The combination of stable domestic prices and a weak Yen creates the highest level of cost-performance in the global market.


Uncompromised Quality at Lower Costs:
Buyers can benefit from reduced costs due solely to currency factors while maintaining the 'Japan Quality' guaranteed by PMDA. This enables healthcare providers to either lower prices for local patients or optimize their own profit margins.


Hedge Against Global Shortages:
A stronger foreign currency budget allows for strategic 'Bulk Buying' to build safety stock. In an era of global pharmaceutical supply instability, leveraging the weak Yen to increase inventory is a powerful strategy to enhance your local Supply Chain Resilience.


Strategic Value of synapse.net

'synapse' provides real-time market data and supply statuses. By integrating these insights, buyers can maximize the advantages of currency fluctuations and execute agile, strategic procurement through Kosei Pharmaceutical's reliable network.

#Weak#Yen#Strategic
Q:What specific benefits does the "Strong Dollar" (USD/JPY) offer international pharmaceutical buyers?
A:

The current 'Strong Dollar' (weak Yen) environment presents a highly strategic opportunity for buyers transacting in USD to maximize procurement quality while significantly reducing costs.


Three Strategic Economic Advantages

Purchasing Power Enhancement:
As the USD gains value against the JPY, your dollar-denominated budget can acquire a significantly larger volume of pharmaceuticals. This increased purchasing power effectively offsets the rising costs of international logistics, maintaining your overall margin.


Expanded Access to High-End Products: High-value Japanese products such as the latest Oncology medications and Orphan Drugs that were previously difficult to budget are now within reach. The lower relative cost allows for the procurement of premium-tier pharmaceuticals without exceeding financial constraints.


Ultimate Cost-Performance Synergy:
The combination of Japan's stable Official Prices (NHI Price) and the strong dollar creates a unique market condition. It allows you to acquire world-class 'Japan Quality' (Trusted, Safe, and High-Purity) at some of the most competitive real-world prices seen in the global market.


Conclusion

In the current market, buyers can dramatically improve procurement efficiency by leveraging currency advantages without compromising on quality or safety. This is a strategic 'buying window' to secure inventory and strengthen your pharmaceutical portfolio under ideal financial conditions.

#weak Yen#NHI Price
Q:What are the procurement benefits of the "Strong Euro" (EUR/JPY) for European buyers?
A:

The current 'Strong Euro' (weak Yen) environment presents a prime strategic opportunity for buyers transacting in EUR to drastically reduce costs while strengthening their pharmaceutical procurement portfolios.


Three Strategic Economic Advantages

Significant Boost in Purchasing Power:
With the Euro strengthening against the Yen, your EUR-denominated budget can acquire a substantially larger volume of pharmaceuticals. For European buyers currently facing high energy and logistics costs, this serves as a powerful mechanism to protect profit margins.


Improved Access to High-Value Products:
Advanced Japanese products-such as cutting-edge Oncology treatments and Orphan Drugs-that may have been previously restricted by budget caps are now more accessible. This allows for a broader range of therapeutic options within existing financial frameworks.


World-Class Cost-Performance:
The combination of Japan's' stable Official Prices (NHI Price) and the strong Euro places buyers in a unique phase where they can acquire 'Japan Quality' (Trusted, Safe, and High-Purity) at a significantly lower real-world cost compared to other international markets.


Conclusion

European buyers can maximize procurement efficiency by leveraging currency advantages without compromising the fundamental pillars of medicine: quality and safety. The current market environment is the 'Optimal Entry Point' for strategically securing reliable Japanese pharmaceuticals for the European market.

#World-Class Cost-Performance#weak Yen#NHI Price
Q:How can I contact you regarding your products or services?
A:

At 'synapse,' we provide two dedicated support channels tailored to your specific needs and current account status.


Support Channel Optimization

Integrated Messaging (For Registered Users)


For specific inquiries regarding an existing quotation or order, please use the 'Messages' feature. This ensures all communication is linked to your transaction history for a faster and more accurate response from our representatives.

Direct Link: https://synapse.net/account/message_rooms/


General Inquiry Form (For New or Non-Logged-in Users)

If you have general questions about our services, wish to discuss a new business partnership, or are experiencing technical system issues, please provide details through our official 'Inquiry Form.'

Direct Link: https://kosei.com/inquiry

#Direct Link
Q:Is it possible to receive support in languages other than English (e.g., Japanese or other languages)?
A:

To ensure the maximum accuracy and professionalism of global medical data, all platform content and customer support services are provided exclusively in English.


Rationale for Our Language Policy

Data Integrity:
In the pharmaceutical field, where highly specialized knowledge is required, we prioritize the prevention of translation-related misinterpretations. This ensures that healthcare professionals worldwide receive identical, clinically accurate data.


Adherence to International Standards:
By utilizing globally recognized English nomenclature-such as INN (International Nonproprietary Names) for active ingredients-we facilitate seamless cross-border research and procurement.


Consistent Global Support:
Our dedicated global team communicates in English to maintain a consistent quality of service and rapid response times, regardless of your time zone or region.

#Consistent Global Support
Q:I entered my company information incorrectly. How can I correct it?
A:

You can modify or update your primary company details-including company name, address, and contact information at any time via the 'My Page' dashboard.


Managing Your Corporate Profile

Access the Dashboard:
After logging in, select 'My Page' from the header menu or sidebar.


Navigate to Company Info:
Click on 'Company Information' to view your current registration details.


Edit and Save:
Click the 'Edit' button to enable editing mode. Correct the necessary fields and ensure you click 'Save' to apply the changes.


Important Considerations

Reflecting Changes in Official Documents:
Updating your profile will not automatically update already issued Quotations or Proforma Invoices (PI). If you require documents to be reissued with the corrected company information, you must contact your representative via the 'Messages' function.

Accuracy for Compliance:
As this information is critical for customs clearance, international trade compliance, and financial transactions, please ensure all entries are accurate and free of spelling errors.

#Navigate to Company Info#Edit and Save#Accuracy for Compliance
Q:Is it possible for individuals (Doctors or Patients) to register an account and purchase products?
A:

Yes. Registration and purchase for personal importation by Doctors or for personal use by Patients are permitted. However, due to the nature of pharmaceutical products, strict legal requirements and credential verifications are mandatory.


Registration Workflow & Required Documentation

  1. System Registration (For Doctors & Individuals):

    • Industry Type: Even when registering as an individual physician or a patient, please select 'Doctor' as the industry type to ensure the process aligns with professional medical oversight.

    • Valid Licenses (Mandatory Uploads)
      • For Doctors: A valid Medical License.
      • For Patients: A valid Prescription issued by your attending physician.

  2. Import Compliance (Country-Specific Regulations):

    The customs and health authorities of the destination country typically require the following documents for clearance:

    • Physician's Letter: An official document justifying the medical necessity of the specific treatment.
    • Prescription: Must clearly state the drug name, dosage, and usage instructions.
    • Patient Acceptance Letter (Self-Usage Declaration): A sworn statement confirming that the medication is for the designated patient's treatment only and not for resale.

IMPORTANT: Local Regulatory Advisory

Regulations regarding the personal importation of pharmaceuticals vary significantly by country. Due to potential restrictions on unapproved drugs or quantity limits, we strongly recommend that you consult with your local health and customs authorities to verify import eligibility before initiating a transaction.

#Industry Type#For Doctors#For Patients
Q:What do the "Categories" represent on the platform?
A:

The 'Categories' on our platform refer to a structured classification system that organizes our extensive pharmaceutical database based on Therapeutic Areas, Pharmacological Actions, and Regulatory Classifications.


Product Classification & Navigation


Primary Categorization Criteria

  • Therapeutic Area: Classification by specific disease groups, such as Oncology, Rare Diseases, or Infectious Diseases.

  • Pharmacological Class: Classification by the drug's mechanism of action, such as Antivirals, Immunosuppressants, or Antibiotics.

  • Product Modality: Differentiation by specialized forms, including Biopharmaceuticals, Small Molecule Drugs, and Orphan Drugs.


How to Use

By clicking the 'Categories' link located directly below the search bar, you can view the full classification list. Selecting a specific domain (e.g., Oncology) allows you to efficiently browse all related products available in the Japanese market.


Benefits of Category-Based Search

  • Comprehensive Research: Even if you do not have a specific product name, you can conduct a broad survey of available Japanese medications within a given therapeutic field.

  • Specialized Filtering: This feature is ideal for medical specialists and procurement officers who need to rapidly assess the latest supply status within their specific field of expertise.

#Therapeutic Area#Pharmacological Class#Product Modality
Q:What do the "Tags" assigned to each product represent?
A:

'Tags' are visual attribute labels that indicate specific logistics requirements, legal regulations, and product classifications for each medication. They are essential for ensuring proper handling and for filtering products based on specific operational criteria.


Attribute Metadata & Regulatory Classifications


Primary Information Conveyed by Tags

  • Logistics & Storage: Indicators such as 'Cold Chain' (2℃ to 8℃) or 'Controlled Room Temperature' (CRT) that signal the need for specialized international transport.

  • Regulatory & Safety Categories: Labels for 'Narcotics,' 'Psychotropics,' or 'Biologics' that require specific export/import licenses and rigorous handling procedures.

  • Product Characteristics: Classifications such as 'Generic' or 'Orphan Drug' to define the product's market status.


How to Use

Click the 'Tags' link located below the search bar to view a complete list of active labels. Selecting a specific tag (e.g., 'Cold Chain') will instantly filter the database to show only products meeting those exact conditions.


Benefits of Using Tags

Proactive Logistics Risk Management: Tags allow you to identify temperature-sensitive or hazardous materials before ordering, making it easier to estimate shipping costs and packaging requirements.

Enhanced Regulatory Compliance: Clearly identify products such as narcotics or psychotropic substances that involve complex import permit processes in your destination country, preventing unforeseen legal delays.

#Logistics & Storage#Product Characteristics#How to Use
Q:How can I find products within a specific therapeutic area using Category Search?
A:

The Category Search function is designed to help you efficiently filter products based on medical domains (e.g., Oncology, Infectious Diseases) and therapeutic applications.


Navigation & Search Logic


Step-by-Step Procedure

  • Access via Link: Click the 'Categories' link located directly below the search bar on the homepage. This will display a comprehensive list of all registered categories.

  • Target Selection: From the list, select the specific medical field you wish to research (e.g., Oncology, Rare Disease, etc.).

  • Review the Product List: The system will generate a tailored list of all Japanese pharmaceuticals belonging to that selected category.


Primary Classification Criteria

  • Therapeutic-Based: Organized according to clinical indications and disease groups.

  • Characteristic-Based: Grouped by product modality, such as Biopharmaceuticals or Orphan Drugs.


Benefits of Utilizing Category Search

  • Comprehensive Domain Coverage: Even if the exact product name is unknown, you can identify all relevant Japanese medications associated with a specific medical discipline.

  • Centralized Supply Insights: It allows you to monitor the latest stock availability and supply statuses (including Shortage alerts) for an entire therapeutic field in one consolidated view.

#Access via Link#Target Selection#Review the Product List
Q:How can I search for products using the Active Ingredient name?
A:

Our platform allows you to search for all relevant products based on their core Active Ingredient (API) using standard English nomenclature.


Component Search Logic & Operations


  1. Incremental Search (Auto-Suggest Feature):

    As you type the first few letters of an active ingredient into the search bar, the system will provide a real-time list of matching candidates. This feature ensures quick and accurate results, even for complex chemical names with difficult spellings.


  2. Active Ingredients List

    By clicking the 'Active Ingredients' link located directly below the search bar, you can access a comprehensive, alphabetized directory of all registered active substances in our database.


  3. Navigation to Product Listings

    Clicking a specific ingredient from the suggestions or the list will generate a tailored view of all pharmaceuticals containing that substance, including both Brand-name drugs and Generic alternatives.


Pro-Tips for Successful Searches

  • Use International Standards (INN): All searches must be conducted in English. We recommend using International Nonproprietary Names (INN) or standard Romanized chemical names.

  • Leverage Partial Matching: Entering even a portion of the ingredient name will trigger the suggestion engine, helping you find the correct substance without needing the full exact spelling.

#Active Ingredients List#Leverage Partial Matching
Q:How can I search for products from a specific pharmaceutical manufacturer?
A:

On 'synapse,' you can filter and browse products from all major Japanese pharmaceutical manufacturers to find exactly what you need based on brand trust and specialized expertise.


Manufacturer Search Logic & Operations


  1. Autocomplete Feature (Search Bar)

    As you begin typing a manufacturer's name in English, the system will display real-time suggestions from our database. Selecting a name from the list grants immediate access to all products manufactured or marketed by that specific company.


  2. Manufacturers List

    Click the 'Manufacturers' link located directly below the search bar to view a comprehensive, alphabetized directory of all registered pharmaceutical companies in our system.


  3. Manufacturer-Specific Product Views

    By clicking a specific company name from the list, you can view their entire lineup including Brand-name drugs, Generics, and Biopharmaceuticals in a single, consolidated view.


Pro-Tips for Successful Searches

Use English Trade Names: All searches must be conducted in English. Please use the official English names of Japanese manufacturers (e.g., Takeda, Astellas, Chugai, Eisai, etc.).

Researching Corporate Strengths: Selecting a specific manufacturer is an excellent way to gain a bird's-eye view of their specialized therapeutic areas, helping you understand their core R&D strengths and supply capabilities.

#Manufacturers List#Search Bar
Q:How can I find products with specific conditions using Tag Search?
A:

The Tag Search function allows you to directly extract products based on specific attributes such as temperature control requirements, legal regulations, and product characteristics.


Attribute-Based Filtering


Step-by-Step Procedure

  • View the Tag List: Click the 'Tags' link located directly below the search bar on the homepage. This will display a comprehensive list of all active tags in the system.

  • Select an Attribute: Choose the specific condition you wish to research from the list (e.g., Cold Chain, Narcotics, Generic, etc.).

  • Review the Results: The system will instantly generate a list of all pharmaceuticals assigned that specific tag.


Key Information Identified via Tags

  • Logistics Category: Temperature management requirements like 'Cold Chain' (2℃ to 8℃).

  • Regulatory Category: Legal handling classifications such as Narcotics, Psychotropics, or Poisonous Drugs.

  • Product Category: Specialized groupings such as Biopharmaceuticals, Orphan Drugs, or Brand-name vs. Generic.


Benefits of Utilizing Tag Search

  • Early Identification of Procurement Risks: You can pinpoint products requiring special export/import permits (e.g., Narcotics) or those impacting shipping costs (e.g., Cold Chain) at the very beginning of your search.

  • Rapid Response to Specific Needs: Tags allow you to instantly meet targeted procurement mandates, such as 'List only high-quality Japanese Generic medicines,' streamlining your sourcing workflow.

#View the Tag List#Select an Attribute#Review the Results
Q:I want to revisit a product I previously viewed. Where can I find my "Browsing History"?
A:

You can easily re-access the history of products you have viewed using any of the following three methods, depending on your location on the site and your device.


Access Methods by Device & Location


  • For Desktop (PC) Users

    Header Icon: Click the 'Clock Icon' (the furthest one on the right in the header row) to go directly to your full history page.
    Homepage: You can view your recently checked products in a slider format within the 'Browsing History' section located mid-way down the homepage.


  • For Mobile Users

    Tap the 'Hamburger Menu' (the three-line icon) in the top-left corner.
    Select 'Browsing History' from the expanded menu list.


Benefits of Using Browsing History

  • Streamlined Research: Return to specific product detail pages with a single click, eliminating the need to re-type complex pharmaceutical names or chemical formulas.

  • Simplified Comparison: Review multiple recently viewed items in a list format to make faster decisions regarding price comparisons or adding items to 'My List' for an estimate.

#Users#Header Icon#Homepage
Q:Where can I access "Company Information" to verify or change my registered corporate details?
A:

The 'Company Information' section is where you manage your official corporate name, address, and contact details, which serve as the primary data for billing and international shipping. Please follow the steps below based on your device.


UI Navigation by Device


For Desktop (PC) Users

  • Click the 'Person/User Icon' (the furthest one on the right in the header row).
    Select 'Company Information' from the dropdown menu.
    Note: You can also access this via the side menu within the 'My Page' dashboard.


  • For Mobile Users

    Tap the 'Hamburger Menu' (the three-line icon) in the top-left corner.
    Select 'Company Information' from the menu list.


Information Managed in This Section

  • Core Corporate Data: Official company name, authorized representative, and Industry Type (e.g., Hospital, Wholesaler, Doctor).

  • Contact & Address Details: Registered head office address and primary telephone numbers used for trade documentation.

  • Uploaded Credentials: Review and manage uploaded verification documents, such as your Medical License or business permits required for pharmaceutical transactions.

#Users#For Mobile Users#Contact & Address Details
Q:How can I search for products (pharmaceuticals)?
A:

On 'synapse,' we utilize a Dual-Search Logic that allows you to either find a specific product via 'Keyword Search' or explore broad options via 'Category & List Browsing.'


The dual logic of search and sourcing


  1. Direct Keyword Search

    Enter any of the following details into the search bar on the homepage and click the 'Magnifying Glass Icon' (or press Enter):

    • Brand Name: The commercial name of the medication (using the Roman alphabet).
    • Manufacturer: The name of the pharmaceutical company.
    • Active Ingredient: The chemical substance name (e.g., INN).
    • Tip: Our 'Autocomplete Feature' will trigger as you type, displaying matching candidates in real-time to help prevent spelling errors.

  2. Browsing via Conditions & Lists

    If you prefer to explore or compare options, use the navigation links located directly below the search bar:

    • Categories: Best for finding drugs by therapeutic area (e.g., Oncology, Rare Diseases).
    • Manufacturers: Best for viewing the complete product lineup of a specific pharmaceutical company.
    • Tags: Best for identifying products with specific attributes, such as 'Cold Chain' requirements or 'Narcotic' classifications.
    • Active Ingredients: Best for comparing different brands or generic alternatives that contain the same core substance.

Pro-Tips for Successful Searching

  • Input in English: Our database is entirely English-based. Please ensure all search queries are entered using the Roman alphabet.

  • Refinement with Search Options: After your initial search, use the 'Search Options' menu to apply granular filters and narrow down your results even further.

#Brand Name#Manufacturer#Active Ingredient
Q:Is it possible to obtain a Certificate of Origin (COO)?
A:

Yes, we can issue a Certificate of Origin. Please request it during the ordering process by following the steps below.


Ordering Process & Document Requests


  • How to Request

    After adding products to your cart, locate the 'Certificate of Origin' checkbox on the Cart Page and ensure it is selected.


  • Issuance Timing

    Once your Order is finalized with the checkbox selected, we will begin preparing the Certificate of Origin in parallel with the shipping process.


  • Important Considerations

    Lead Time: Since issuance may require procedures with external organizations such as the Chamber of Commerce, several additional business days may be added to the standard shipping schedule.

    Costs: Separate issuance fees or Legalization (Notary) fees may apply. Please verify the specific conditions within your cart or the terms provided in your quotation.


Pro-Tips for Trade Documentation

  • Specific Formats: If your destination country requires a specific form or a Consular Invoice, please consult with us in advance via the Messages feature or the Inquiry Form.

  • Hard Copy vs. Soft Copy: We recommend confirming whether you require the physical original (Hard copy) by mail or if a digital version (Soft copy/PDF) is sufficient for your local customs clearance.

#Issuance Timing#Costs#Soft Copy
Q:Can you translate the Package Insert (Prescribing Information) into English or other languages?
A:

We apologize, but we do not provide translations or multilingual versions of the Package Insert.


Logic for Safety and Compliance


  • Importance of Safety Information

    The Package Insert contains critical data directly linked to patient safety and life, such as Side Effects, Contraindications, and Dosage and Administration.


  • Mitigating Translation Risks

    In medical communication, even a minor nuance error in translation can lead to severe medical accidents. Prioritizing safety above all, we handle only the manufacturer's original text as the official document to prevent any alteration of information caused by secondary translations.


  • How to Access Information

    Please refer directly to the original version in the official language provided with the product, or consult the official documents and resources published by the manufacturer on their website.

#Mitigating Translation Risks
Q:Is it possible to receive photos of the product packaging (outer box) before purchasing?
A:

Yes, we will respond as flexibly as possible. However, the availability of photos depends on the product's inventory status and supplier constraints.


Physical Verification: Flexibility and Constraints


  • Available Cases

    For products currently in our stock or those we handle on a regular basis, we can provide actual photos of the product packaging.


  • Restricted or Delayed Cases

    For medications we are handling for the first time or 'On-request items' (ordered from suppliers only after receiving your request), we cannot confirm the physical product until it arrives at our facility. Therefore, pre-shipment photos may not be immediately available.


  • Content Provided

    Generally, we provide photos of the entire outer package. If you require verification of a specific Batch Number (Lot No.) or Expiry Date, this may only be possible during the inspection phase after the order is finalized.


How to Request Photos

If you require photos for customs pre-clearance or to verify specific product specifications, please send a request via Messages or the Inquiry Form. Please include:

  • The Product Name

  • The Specific Area to be Photographed (e.g., active ingredient list, barcode section, etc.)

#Physical Verification#Restricted or Delayed Cases#Content Provided
Q:Can I request a temperature logger to monitor the products during transit?
A:

Yes, temperature loggers are available as a paid option. This ensures full traceability and guarantees product quality during the transportation of temperature-sensitive pharmaceuticals.


Temperature Management Logic & Cost Structure


  • Service Overview

    We place a temperature data logger inside the shipping container to record temperature fluctuations from the moment of dispatch to delivery. Upon arrival, the data can be retrieved to verify that the required temperature range (e.g., 2℃ to 8℃) was strictly maintained.


  • Fee Structure

    The use of a logger is an optional service. Costs vary depending on whether it is a rental unit or a single-use disposable device.

    How to Request: Select the logger option on the Cart Page (or the final confirmation screen) before finalizing your order. Alternatively, you can request it directly from your representative via Messages.


  • Types of Loggers

    We select the most appropriate device (e.g., USB-readable or Cloud-linked) based on the destination and the expected duration of transit.


Benefits of Using a Data Logger

  • Quality Assurance: Provides objective, data-driven proof of product stability upon arrival.

  • Risk Management: In the event of transit delays or external issues, the logger allows for an accurate assessment of any potential impact on the medication's efficacy.

#Fee Structure#How to Request#Types of Loggers
Q:What are PIL (Package Information Leaflet) and SmPC (Summary of Product Characteristics)?
A:

These refer to the Package Insert (comprehensive information materials including labeling and prescribing information). Our platform provides these official documents in their original Japanese format, covering the following essential data:


  • Mechanism of Action, Indications, and Usage

  • Dosage and Administration

  • Contraindications, Warnings, and Precautions

  • Adverse Reactions and Safety Information

  • Storage Conditions and Expiration Dates

  • Our Policy on Translation and Safety


Regarding English translations: In medical communication, even a minor nuance error in translation can lead to severe medical accidents.

To prioritize patient safety and prevent any alteration of information caused by secondary translations, we handle only the manufacturer's original Japanese text as the sole official and authentic document. We do not provide in-house translations to ensure the absolute integrity of the medical data provided by the pharmaceutical companies.

#These#Package#Insert
Q:What exactly does "Licenses" refer to on this platform?
A:

In the context of 'synapse,' Licenses refer to the official business permits issued by national regulatory authorities (such as the Ministry of Health, Labour and Welfare in Japan or the FDA/EMA in other regions). These are mandatory for the proper and safe handling of pharmaceuticals and medical devices.


Systematic Understanding of Pharmaceutical Licenses


The distribution of pharmaceuticals is strictly regulated by law, requiring appropriate licenses based on the specific role of the business (manufacturing, importing, or selling). Key examples include:


  • Wholesale License:

    Required for wholesaling pharmaceuticals to medical institutions or other authorized distributors.


  • Manufacturing License:

    Required for the production or final packaging/labeling of medicinal products.


  • Import License:

    Required to legally import pharmaceuticals from overseas and distribute them within a specific domestic market.


  • Pharmacy / Medical Institution License:

    Required for pharmacies or hospitals to dispense and prescribe medications directly to patients.


Why is the submission of these licenses mandatory?

Because pharmaceuticals directly impact human life, global trade is legally permitted only between 'Authorized Entities' who possess valid qualifications.

By verifying that every user on 'synapse' holds the appropriate licenses, we ensure strict compliance with international laws.
This process is vital for:

  • Preventing the infiltration of counterfeit medicines.

  • Building a secure and transparent supply chain.

  • Guaranteeing the integrity of the products being traded.

#Key examples include#Wholesale License#Manufacturing License
Q:Is it possible to obtain a CoA (Certificate of Analysis) for a product?
A:

We apologize, but we do not provide a Certificate of Analysis (CoA). Our policy is based on the following pharmaceutical quality assurance standards.


Quality Assurance & Information Integrity


  • Strict Manufacturer Control

    A CoA is a quality certificate issued by the pharmaceutical manufacturer for each specific production batch. These are highly confidential documents usually disclosed only to direct primary distributors.

  • Integrity of the Distribution Process

    Our primary mission is to deliver products while maintaining the original quality guaranteed by the manufacturer. Since we do not perform independent laboratory testing, we do not issue analysis certificates under our own name.


How Quality is Guaranteed

The quality and authenticity of the product are managed and guaranteed by the Expiry Date and Batch/Lot Number printed on the original manufacturer's packaging. If you require detailed chemical analysis data, we recommend contacting the manufacturer directly using these identifiers.

#We#Certificate#Analysis
Q:Who is responsible for creating the "Invoice" required for import and export?
A:

We (the shipper) handle the creation and arrangement of all necessary invoices. You do not need to prepare these documents yourself.


Responsibility and Expertise in Documentation


  • Our Scope of Support

    We prepare the Commercial Invoice (CI) and Packing List (PL) essential for international transport, ensuring they are formatted to comply with global customs regulations.


  • Accuracy of Information

    To facilitate smooth customs clearance for pharmaceuticals, we ensure that all details including the official product name, quantity, unit price, Incoterms (trade terms), and country of origin are accurately recorded.


  • Digital Accessibility

    Once the shipment is complete, you can view and download the generated invoice in PDF format from your Order History on My Page.


Pro-Tips for Trade Operations

  • Proforma Invoice (PI): If you require a 'provisional invoice' for payment procedures (such as obtaining a wire transfer permit) before finalizing your order, please request one via Messages.

  • Special Requirements: If your country's regulations require specific declarations, additional wording, or Notarization/Legalization, please consult us in advance. We are happy to accommodate these requests to ensure compliance with your local laws.

#Accuracy of Information#Digital Accessibility#Special Requirements
Q:Is it possible to negotiate a discount on product prices?
A:

We apologize, but we do not accept individual price negotiations. We are committed to providing every customer with our best, fair, and consistent pricing at all times.


Pricing Policy & Reliability Logic


  • Commitment to Transparency and Fairness:

    Our prices are calculated based on the actual costs of procurement and the rigorous quality maintenance required for pharmaceuticals (such as strict temperature control and specialized logistics). To maintain high transparency, we offer the most competitive price upfront without variations between different customers.


  • Prioritizing Quality and Supply Integrity:

    Given the life-critical nature of pharmaceutical products, we prioritize guaranteed sourcing and comprehensive quality management over aggressive price competition. This ensures that the products you receive are handled with the highest level of professional care.

#We#Pricing#Policy
Q:If I request a quote for a pharmaceutical product, is its availability guaranteed once I order?
A:

No. Unfortunately, we cannot guarantee 100% availability. The supply status of the pharmaceutical market fluctuates constantly, and products may become unavailable even after a quotation has been issued.


Supply Chain Volatility & Risk Management


  • Primary Reasons for Limited Availability:

    • Drug Shortages: Supply from manufacturers may stop abruptly due to raw material shortages, production line halts, or sudden surges in global demand.

    • Discontinuation: Manufacturers may cease production of a product at their discretion without prior notice.

    • Export Restrictions: Changes in political climate or legal regulations in the country of origin may temporarily restrict international shipments.


  • Our Inventory Commitment

    While we verify stock and procurement prospects at the time of quotation, physical inventory moves in real-time. Product allocation is finalized only upon 'Completion of Payment.' Therefore, an item may sell out between the time a quote is issued and the time payment is received.


Process If a Product Cannot Be Sourced

In the unlikely event that a product is found to be unavailable after your order is confirmed, we will promptly take the following actions:

  • Proposal of Alternatives: We will suggest generic versions with the same active ingredients or alternative medications with equivalent therapeutic effects.

  • Full Refund: If an alternative solution is not feasible, we will immediately initiate a full refund process for the affected item.

#Drug Shortages#Discontinuation#Export Restrictions
Q:Is it possible to "re-order" (repeat purchase) products I have bought before?
A:

Yes. For products purchased within the past year, you can quickly re-order them at the same price as your previous transaction, bypassing the standard quotation process.


Re-order Conditions and Operational Flow


  • Access the 'Purchase Now' Page

    Navigate to your personalized re-order list via the following methods:

    • On PC: Click the 'Purchase Now' (shopping bag icon), located fourth from the right in the top header.

    • On Smartphone: Tap the menu button (three-bar hamburger menu) at the top left and select 'Purchase Now.'

    • Home Page: You can also access it directly via the 'Purchase Now' button on the main dashboard.


  • Steps to Re-order

    1. Find the product in your list and click the checkbox to the left of the product photo.

    2. Click the 'Add to cart' button to move the items to your shopping cart.

    3. Proceed to the cart page, verify your shipping and payment details, and complete your order.


Advantages and Important Considerations

  • Price Guarantee: For one year following your initial purchase, you can re-order at the same price, regardless of fluctuations in currency exchange rates or market prices.

  • Expiration: Products not purchased for more than one year will be removed from the list or require a new quote. In this case, please submit a new request via the 'Quotes' page.

  • Inventory Availability: While the price is locked, the actual availability of the product depends on current market conditions. In the event of a global drug shortage, the item may be temporarily unavailable.

#Page#On PC#On Smartphone
Q:How do I add products to the cart and change the quantity?
A:

To ensure the most accurate availability of pharmaceuticals, our platform follows a specific flow: 'Request a Quote first, then add to Cart after receiving our response.'


Ordering Flow and Operational Steps


  1. Requesting a Quote (For New/First-time Items):

    Select the desired pharmaceutical and complete the 'Request Quote' process. We will verify procurement feasibility and send you a quotation response email.


  2. Adding to Cart and Adjusting Quantity

    Once the quotation is completed, the products will be available for purchase.

    • Quantity Change: You can adjust the number of items in the quantity input field within the Cart screen.

    • Confirmation: After setting the quantity, click the 'Continue' button to proceed to the payment instructions (Bank Transfer details).


  3. Re-ordering (For Items Purchased Within the Past Year):

    For products bought within the last 12 months, you can bypass the quotation step. Go to the 'Purchase Now' (Re-order list), check the boxes for the desired items, and click 'Add to Cart.'


Operational Tips

  • Verifying Quote Responses: Products will not appear in your cart until the quotation response is finalized. You can monitor the progress on the 'Quotes' (Quotation History) page.

  • Bulk Checkout: If you have multiple quotation responses, you can combine them in the cart and process them as a single order for a more efficient transaction.

#Quantity Change#Confirmation#Bulk Checkout
Q:Can I add new products to an order that has already been placed (Awaiting Payment / Processing)?
A:

Yes, this is possible as long as the payment has not been finalized. However, rather than simply modifying the existing order, the process requires a 'Re-quote and Re-order' procedure. Please contact us immediately via Messages or Email.


Process and Impact of Adding Products to an Existing Order


  • How We Handle Requests

    Our system does not allow direct editing of an order once it has been confirmed. We will issue a new quotation that reflects the total updated amount, including the additional products.


  • How to Contact Us

    Please use the Messages room associated with your order and specify the 'Order No.' along with the 'Product Name and Quantity' you wish to add.


  • Important Note Regarding Delays

    Adding items may cause a delay of one week or more in shipment for the following reasons:

    • Re-issuance of Documents: All export documentation including the Commercial Invoice, Packing List, and customs forms must be entirely recreated.

    • Re-securing Inventory: Additional time is required to procure and inspect the newly added items.

    • Payment Adjustment: If a transfer has already been initiated, an additional remittance for the price difference will be required.


For Smooth Processing

If the payment has already been confirmed and the shipping process is underway, we may not be able to add items to the current order. In such cases, please place a separate new order.

#How to Contact Us#Re-issuance of Documents#Re-securing Inventory
Q:Is it possible to have the products shipped before payment? (Do you offer deferred payment?)
A:

We apologize, but all transactions are conducted on a '100% Advance Payment' basis. We begin the procurement of products and preparation for shipment immediately once your payment has been confirmed.


Rationale Behind Advance Payment and Its Benefits


  • Ensuring Stock Availability and Price Stability:

    The pharmaceutical market is highly volatile, with frequent price fluctuations and rapidly changing inventory levels. By requiring payment upfront, we can immediately secure the stock from manufacturers or wholesalers, ensuring that we honor the delivery timeline and unit price provided in your quotation.


  • International Trade Compliance

    The cross-border distribution of pharmaceuticals involves strict export/import regulations and complex customs procedures. To prevent fraudulent transactions and guarantee the reliable fulfillment of every order, we apply a uniform advance payment policy for all users.


  • Workflow to Shipment

    • Please remit payment to the account specified in your PI (Proforma Invoice).

    • Notifying us via Messages after completing the transfer can help expedite the verification process.

    • Once the funds are confirmed, your order transitions immediately into the shipping process.


Tips for a Smooth Transaction

  • For Urgent Orders: Bank transfers can sometimes take time to reflect in our system. If your order is time-sensitive, please send a photo or scan of your transfer receipt. This may allow us to begin procurement preparations in advance of the official fund reflection.

  • Continuous Business: Please be advised that advance payment is required for every individual order, regardless of your past transaction history with us.

#Workflow to Shipment#Continuous Business#Proforma Invoice
Q:Do active ingredient names (Generic Names) support foreign languages or international notations?
A:

As a general rule, active ingredient names on our platform are standardized to 'U.S. Notation (USAN / USP)' only.


Ensuring Search Precision and International Standardization


  • Why We Adopt U.S. Notation

    By adopting USAN (United States Adopted Names) the most standard and widely utilized nomenclature in the global pharmaceutical trade we prevent naming inconsistencies, maintain high search accuracy, and ensure the integrity of our database.


  • Important Search Considerations

    Differences between U.S. and UK/EU Notations: Please be aware that spellings may differ from British English (INN / BP).

    • Example: U.S. 'Epinephrine' vs. UK 'Adrenaline'

    • Example: U.S. 'Acetaminophen' vs. UK 'Paracetamol'


  • Japanese and Other Local Languages:

    Searching by Japanese ingredient names or other local languages is currently not supported.


Advice for Successful Searching

  • Verify USAN Spellings: If you cannot find a specific ingredient, please verify the U.S. notation (USAN) and try again. If you are unsure of the correct spelling, feel free to contact us via Messages, and our specialists will assist you.

  • Utilize CAS Numbers: For precise identification of chemical substances, providing the CAS Registry Number in your quotation request is the most reliable method.

  • Identify via Brand Names: If you provide a well-known brand name (Innovator drug), our team can cross-reference it with the standardized U.S. generic name for you.

#Notation#EU Notations#Example
Q:Do you handle psychotropic drugs?
A:

We apologize, but we do not handle any products classified as psychotropic drugs, narcotics, stimulants, or their precursor raw materials.


Regulatory Compliance and Safety Management


  • Reason for Exclusion: Strict Legal Restrictions

    The import, export, and domestic distribution of psychotropic substances are strictly limited to specific licensed entities under the 'Narcotics and Psychotropics Control Act' of Japan and the international 'Convention on Psychotropic Substances.' To maintain the highest standards of legal compliance, we exclude all products within these regulatory categories from our lineup.


  • Key Restricted Categories

    • Psychotropic drugs (Schedule I, II, and III)

    • Narcotics, Opium, and Stimulants

    • Designated Substances (under the PMD Act)


  • Notice to Customers

    If you are unsure whether a desired ingredient falls into these restricted categories, please verify with your local regulatory authorities or professional institutions before requesting a quote. If a requested item is found to be a regulated substance, we will be unable to provide a quotation.


Advice Regarding Procurement

  • Consideration of Alternative Ingredients: You may still request quotes for non-regulated alternative ingredients or pharmaceuticals in other categories that may offer comparable efficacy.

  • Importance of Non-Applicability Certificates: If you require documentation proving that a specific ingredient is 'Not Applicable' to these restricted categories for customs clearance, please consult our specialists via Messages.

#Strict Legal Restrictions#Key Restricted Categories#Notice to Customers
Q:Do you handle injectables (Parenteral drugs)?
A:

Yes, we handle various types of injectables, including vials, ampoules, and pre-filled syringes. Because these are extremely delicate products, we maintain strict quality control and specialized transport protocols.


Quality Assurance for Sterile Preparations


  • Primary Product Forms Handled

    • Vials: Powder-filled or liquid solutions.

    • Ampoules: Liquid medications in sealed glass containers.

    • Pre-filled Syringes (PFS): Ready-to-administer medication pre-loaded in syringes.

    • IV Bags: Large-volume parenterals for infusions.


  • Safety and Quality Control (GDP Compliant):

    As sterile preparations administered directly into the bloodstream or tissues, injectables require maximum protection against vibration, light exposure (photosensitivity), and temperature fluctuations. We implement the following measures:

    • Temperature-Controlled Logistics: For injectables requiring refrigeration (2℃ to 8℃), we strongly recommend high-performance insulated containers (e.g., va-Q-tec).

    • Medical-Grade Cushioning: To prevent breakage (such as glass fractures) during transit, we utilize medical-standard shock-absorbent packaging.


Professional Advice for Procurement

  • Preventing Temperature Excursions: Many injectables, particularly biologics, lose their efficacy immediately if frozen or exposed to high temperatures. We highly recommend the use of temperature data loggers for secure transit verification.

  • Verification of Required Documents: Importing injectables may require specific certificates or detailed ingredient lists depending on the destination country. Please consult our specialists via Messages for tailored support.

#Vials#Ampoules#IV Bags
Q:Do you also handle health foods (supplements or non-pharmaceutical products)?
A:

We apologize, but we do not currently handle health foods or dietary supplements. At present, our services are specialized in the procurement and quality control of high-specification pharmaceuticals.


Current Strategic Focus and Future Outlook


  • Current Scope of Services

    Our primary focus is on Ethical Pharmaceuticals (Prescription Drugs) and Clinical Trial Materials, both of which require rigorous temperature management and strict regulatory compliance.


  • Future Expansion Plans

    Expanding our lineup to include health foods and functional foods is part of our future service roadmap. We will promptly announce any updates regarding the commencement of these services via our official news releases and member newsletters.


  • Inquiries for Similar Products

    Please note that certain vitamin preparations or nutritional supplements classified as pharmaceuticals due to their active ingredients may be available. We encourage you to verify the active ingredient name (USAN) and submit a 'Request Quote.'


Message to Our Users

  • Commitment to Specialization: By leveraging the logistical expertise gained in the highly demanding pharmaceutical sector, we aim to provide the same world-class delivery and management standards when we expand into health foods in the future.

  • Requesting New Items: If you have specific health foods or ingredients you would like us to handle in the future, please share your requests via Messages. Your feedback will be a valuable reference for our lineup expansion.

#Future Expansion Plans#Requesting New Items#Prescription Drugs
Q:Are the pharmaceuticals provided the latest batches (with sufficient shelf life)?
A:

Yes. We implement rigorous inventory and procurement management to ensure that we always deliver products from the 'latest manufacturing batches' with a 'sufficient expiry date.'


Product Freshness and Quality Assurance


  • On-Demand Procurement for Maximum Freshness:

    For many of our products, we utilize a 'Just-in-Time' procurement system, placing orders with manufacturers or authorized wholesalers only after your payment is confirmed. This eliminates the risk of shelf-life degradation due to long-term storage and ensures you receive the freshest lots currently available in the market.


  • Advance Verification of Expiry Dates

    When you submit a 'Request Quote,' we verify the Expiry Date (EXP) of the currently available lots. This information can be provided during the quotation phase upon request.


  • Strict Quality Control (FEFO Principle):

    For items held in our own inventory, we adhere to the international pharmaceutical standard of FEFO (First-Expired, First-Out). This ensures optimal stock rotation and maintains the highest standards of product freshness.


Advice for Our Users

  • Specific Shelf-Life Requirements: If your research project or long-term administration plan requires a specific minimum shelf life (e.g., 'at least 12 months remaining'), please specify this in the remarks section of your quotation request.

  • Inspection Upon Arrival: Always verify the 'EXP (Expiry Date)' and 'Batch/Lot No.' printed on the outer packaging and the immediate container of the delivered product.

#Inspection Upon Arrival#FEFO Principle#Expiry Date
Q:Can you inform me of the expiry date of the product before I make a purchase?
A:

Yes. For every quotation request, we investigate and provide the expiry date of the latest available lot that can be secured at that specific moment.


Dynamic Inventory Management and Information Accuracy


  • The Reason for 'Case-by-Case' Verification:

    Expiry dates vary by manufacturing batch, and market inventory is highly fluid. To ensure that we always deliver the 'freshest possible product' to our customers, we verify the latest stock status with manufacturers and authorized wholesalers at the exact time of your inquiry.


  • Timing of Disclosure

    After you submit a 'Request Quote,' we will specify the 'Expiry Date (EXP)' of the target product within our formal quotation response.


  • Guarantee of Shelf Life

    We ensure that all delivered products have a sufficient period for standard use (ranging from several months to years, depending on the product). In the unlikely event that the only available market stock has an unusually short shelf life, we will explicitly inform you during the quotation phase and proceed only after receiving your consent.


Advice for Our Users

  • When a Specific Expiry Date is Required: If your requirements are strict (e.g., 'Must have at least 12 months remaining due to a specific research period'), please state this in the remarks section when requesting a quote. We will prioritize searching for a lot that meets your criteria.

  • Verification Upon Receipt: Once the product arrives, please re-confirm the 'EXP (Expiry Date)' printed on the outer packaging.

#Verification#Timing of Disclosure#Guarantee of Shelf Life
Q:Can I receive a sample (free trial) of a pharmaceutical product?
A:

We apologize, but in accordance with the nature of pharmaceutical products and international legal regulations, we do not provide samples under any circumstances.


Legal and Practical Background for No-Sample Policy


  • Compliance with Pharmaceutical Laws and International Regulations:

    Pharmaceuticals must be used under the supervision of a physician or with a valid prescription. The free distribution of samples for promotional purposes is strictly regulated or prohibited in many countries. To maintain the highest level of compliance, we do not fulfill requests for samples regardless of the reason.


  • Quality Assurance (GDP) and Traceability:

    Every product we deliver is subject to rigorous temperature control and end-to-end traceability from the manufacturer to the customer. Distributing portions as samples is not permitted, as it compromises our ability to guarantee the quality and chain of custody of the medication.


  • Support for Your Evaluation

    If you need to verify product specifications, active ingredient concentration, standards, expiry dates, or require a copy of the Certificate of Analysis (CoA), please contact us via Messages. We will provide as much technical information as possible to assist your purchasing decision.


Advice for Our Users

  • Purchase the Smallest Unit: If you are introducing a product for the first time and wish to verify its suitability, please specify the 'Minimum Package Unit' (e.g., one box or one bottle) in your quote request. We recommend starting with a single-unit purchase.

  • Refer to Scientific Documentation: We encourage you to review the product information on our site or the Package Insert (Prescribing Information) available on the manufacturer's official website prior to ordering.

#and Traceability#Support for Your Evaluation
Q:If a product is marked with "We can't handle this product," will I still receive a response if I request a quote?
A:

We apologize, but for products displaying this message, we are currently unable to provide quotations or facilitate procurement.


Reasons for Handling Restrictions and System Limitations


  • Meaning of the Message

    Items marked with this status have been identified as difficult to deliver reliably and safely through our current network for the following primary reasons:

    • Import/Export Regulations: This includes psychotropic drugs, narcotics, or ingredients requiring extremely strict import licenses in the destination country.

    • Supply Route Unavailability: Cases where the manufacturer has discontinued supply or the product is restricted to specific regional sales channels.

    • Physical and Quality Constraints: Items requiring highly specialized storage conditions that fall outside what can be guaranteed under our current GDP (Good Distribution Practice) standards.


  • System Behavior

    For these products, the 'Request Quote' button is typically disabled. If a request is somehow submitted, the system is designed to automatically restrict the response as 'Unavailable.'


Advice for Our Users

  • Explore Alternatives: Even if a specific item is unavailable, products with the same active ingredient from a different manufacturer or in a different dosage/concentration may be available. Please check other variations in the search results.

  • Market Fluctuations: Availability may change in the future due to the easing of regulations or the securing of new procurement routes.

  • Consultation for Critical Needs: If that specific ingredient is absolutely essential for your needs, please contact us via Messages with details (intended use, required quantity, and destination). Our specialists will conduct a re-investigation to see if an individual solution can be found.

#Export Regulations#Supply Route Unavailability#System Behavior
Q:Are all pharmaceuticals distributed in Japan listed on the website?
A:

Yes, we cover nearly all types of pharmaceuticals approved and distributed within Japan. However, certain products such as those prohibited from air transport for safety reasons are excluded from the listings.


Database Comprehensiveness and Rational Logistics Restrictions


Comprehensive Database Coverage

Our platform is linked with Japan's major pharmaceutical databases, providing up-to-date information on the latest National Health Insurance (NHI) price-listed items, including both innovator (brand-name) drugs and generics.

Excluded Products (Air Transport Restrictions):

Based on international safety standards, such as the IATA Dangerous Goods Regulations (DGR), pharmaceuticals with the following properties may not appear in search results because maintaining quality or ensuring safe transport is difficult:

  • High-Pressure Gas Products: Aerosols or certain inhalers that pose an explosion or flammability risk.

  • Flammable Liquids: Products with high alcohol concentrations classified as 'Dangerous Goods.'

  • Corrosive or Toxic Substances: Items that pose a risk of severe damage to the aircraft or other cargo in the event of a leak.

  • Other Restricted Items: Products with strong magnetic properties or radiopharmaceuticals.


Advice for Our Users

  • If You Cannot Find a Product

    If a desired product is not found, it may be due to the transport restrictions mentioned above, or there may be a discrepancy in spelling or specifications. Please contact us via Messages with the product name or JAN code.

  • Verifying Alternative Logistics

    Even for items not listed, our specialists can conduct an individual investigation to see if transportation is possible via specialized routing or enhanced packaging.

#High-Pressure Gas Products#Flammable Liquids#Corrosive or Toxic Substances
Q:Do you handle OTC (Over-the-Counter) drugs?
A:

We apologize, but at this time, we do not handle OTC (non-prescription) drugs. Our current services are specialized in Ethical Pharmaceuticals (Prescription Drugs) that require advanced management and regulatory oversight.


Future Roadmap and Supply Strategy


  • Upcoming Expansion

    The inclusion of OTC drugs is part of our near-future service expansion roadmap. We plan to sequentially introduce major, highly reliable Japanese OTC brands to our platform.


  • Current Focus

    Our primary mission is the stable supply of Ethical Pharmaceuticals (Innovators and Generics), which demand rigorous temperature control, strict legal compliance, and the provision of detailed pharmacological data.


  • Notification Settings

    Once OTC products become officially available, we will promptly notify all members via official news releases and our email newsletter.


Professional Advice for Users

  • Specific Product Requests: If you have specific OTC brands or active ingredients that you require on a regular basis, please share your requests via Messages. Your feedback will directly influence our priority list for lineup expansion.

  • Distinguishing from Ethical Versions: In many cases, the same active ingredient is available in both OTC and Ethical (Prescription) versions. If the product you are seeking exists as an Ethical drug, you can search for it and request a quote using the Active Ingredient Name (USAN).

#Current Focus#Notification Settings#non-prescription
Q:Do you handle Veterinary Medicines?
A:

Yes, we provide a wide range of veterinary medicines. While we are currently in the process of listing these products on our website, we can already provide quotations and facilitate procurement upon request.


Sourcing Flow for Veterinary Products (Pre-System Integration)


  • Current Ordering and Quotation Method

    Until the system integration is complete, some veterinary products may not appear in the search results. If you require a quote, please contact us directly via Messages with the following information:

    • Product Name: (Brand name or Active Ingredient)

    • Specifications/Capacity: (e.g., 5mg x 28 tablets, 10ml vial, etc.)

    • Required Quantity


  • Future Integration

    A dedicated Veterinary Medicines category will be integrated into our searchable database in the near future. Once integrated, you will be able to submit a 'Request Quote' directly from the site, just as you do for human pharmaceuticals.


  • Commitment to Quality Control

    Our veterinary products are handled with the same rigorous GDP (Good Distribution Practice) standards as human pharmaceuticals, ensuring strict temperature control and sourcing only from reliable, authorized channels.


Professional Advice for Users

  • Regulatory Verification: Depending on the destination country, specific licenses or prescriptions may be required to import veterinary medicines. If you have concerns regarding local import regulations, please consult our specialists via Messages.

  • Specialized Sourcing Requests: We can utilize our global network to search for specific veterinary formulations or rare veterinary products from particular manufacturers.

#Product Name#Capacity#Required Quantity
Q:How can I check if a specific product is available for handling?
A:

Please check the search results or the product detail page. You can request a quote for any product that does not display the message 'We can't handle this product.'


Criteria for Determining Availability


  1. If 'We can't handle this product' is displayed:

    We regret to inform you that we are currently unable to handle these items due to legal regulations (e.g., narcotics/psychotropics), air transport restrictions (IATA), or the lack of a stable supply route. We are unable to provide quotations for these products at this time.

  2. If the above message is NOT displayed (or a 'Request Quote' button is present):

    The product is available for handling. Please specify the quantity and specifications and submit a 'Request Quote.' We will calculate and provide the latest pricing and lead time in our response.

  3. If the product is not found in the search results:

    The product may not be listed in our database yet or may be temporarily hidden. In such cases, please contact us directly via Messages with the 'Product Name,' 'Active Ingredient,' and 'Specifications.' Our specialists will conduct an individual investigation into its availability.


Tips for Smooth Verification

  • Check for Alternatives: Even if a specific product is marked as 'We can't handle...,' other variations such as a different manufacturer or a different dosage/concentration are often available for quotation.

  • Information Updates: Availability status is updated daily based on changes in local laws and supplier conditions. A product that was unavailable in the past may be available now.

#is displayed#Information Updates#IATA
Q:Are the images of product packaging and PTP sheets shown on the site the latest versions?
A:

We update product images regularly. However, due to sudden design changes (rebranding) by manufacturers or differences in regional language specifications, the actual product you receive may temporarily differ from the image shown.


Guidelines on Image Alignment and Product Consistency


  • Image Update Policy

    We sequentially replace images with newer versions as new manufacturing batches arrive. However, as we handle a vast global inventory, some products may still display previous designs or utilize representative images for specific dosage forms.


  • Primary Reasons for Packaging Variations:

    • Manufacturer Rebranding: Cases where the outer box design is updated to improve visibility or enhance anti-counterfeiting measures, while the active ingredient and efficacy remain unchanged.

    • Destination (Regional) Variations: Cases where the same product has different packaging languages or designs depending on the country or region of supply.

    • Specification Differences: Cases where the color or shape of the PTP (Press Through Package) sheet varies based on the quantity (e.g., 10-count vs. 28-count packs).


  • Guarantee of Product Identity

    Regardless of differences in external appearance, we guarantee that all products provided are authentic pharmaceuticals with active ingredients and specifications that match your order.


Professional Advice for Users

  • Verification of Appearance: If you require a specific package design or wish to see a photo of the current stock before purchasing, please contact us via Messages. We will provide a photograph of the actual product whenever possible.

  • Authenticity Confirmation: If you have any concerns about the product you received, please provide us with the 'Batch/Lot No.' printed on the package. We will verify the sourcing route and provide a formal confirmation.

#Manufacturer Rebranding#Variations#Specification Differences